It took a little more work to get this working for me. To get the browser version working in our dev domain on a vanilla 2008 R2 IIS server, i did the following.
After setting up the setup.zip contents as a folder in ISS default web site, in addition to configuring the default file, I also needed to:
IIS \request filtering - remove .config file from deny list
IIS\Authentication - disable anonymous and enable windows authentication
After this was done, the web application installed and the client centre opened and worked great!